產(chǎn)品詳情
簡(jiǎn)單介紹:
NuclearCapBindingProteinSubunit1,80kDa(NCBP1)(N-Term)Peptide
詳情介紹:
Blocked Antibody | anti-Nuclear Cap Binding Protein Subunit 1, 80kDa (NCBP1) (N-Term) antibody (ABIN2778796) |
Characteristics | This is a synthetic peptide designed for use in combination with anti-NCBP1 antibody (Catalog #: ARP40396_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. |
Purification | Purified |
Background |
NCBP1 is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. The encoded protein promotes high-affinity mRNA-cap binding and associates with the CTD of RNA polymerase II. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay.The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. The encoded protein promotes high-affinity mRNA-cap binding and associates with the CTD of RNA polymerase II. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. Alias Symbols: CBP80, MGC2087, NCBP, Sto1 Protein Interaction Partner: EIF4G1,EIF4G2,NCBP2,STAU1,BNIP1,BNIP3,EIF4G1,EIF4G2,HNRNPF,HNRNPH1,NCBP2,RNF40,RPS6KB1,SNRPA1,STAU1,BNIP1,BNIP2,BNIP3,EIF4G1,HNRNPF,HNRNPH1,NCBP2,RNF40,SRSF9 Protein Size: 790 |
Molecular Weight | 92 kDa |
Gene ID | 4686 |
NCBI Accession | NM_002486, NP_002477 |
UniProt | Q09161 |
Research Area | DNA/RNA, Chromatin and Nuclear Signaling |
Application Notes | Each Investigator should determine their own optimal working dilution for specific applications. |
Restrictions | For Research Use only |
Format | Lyophilized |
Reconstitution | Add 100?μL of sterile PBS. Final peptide concentration is 1?mg/mL in PBS. |
Concentration | 1 mg/mL |
Buffer | Final peptide concentration is 1 mg/mL in PBS. |
Handling Advice | Avoid repeated freeze-thaw cycles. |
Storage | -20 °C |
Storage Comment | For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles. |