產品詳情
簡單介紹:
LysylOxidase-Like1(LOXL1)(MiddleRegion)Peptide
詳情介紹:
Blocked Antibody | anti-LOXL1 antibody (Lysyl Oxidase-Like 1) (Middle Region) (ABIN2785879) |
Characteristics | This is a synthetic peptide designed for use in combination with anti-LOXL1 antibody (Catalog #: ARP54781_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. |
Purification | Purified |
Background |
LOXL1 is a member of the lysyl oxidase family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. Alias Symbols: LOL, LOXL Protein Interaction Partner: ELN,FBLN5,FBLN5 Protein Size: 574 |
Molecular Weight | 53 kDa |
Gene ID | 4016 |
NCBI Accession | NM_005576, NP_005567 |
UniProt | Q08397 |
Research Area | Metabolism, Amino Acids |
Application Notes | Each Investigator should determine their own optimal working dilution for specific applications. |
Restrictions | For Research Use only |
Format | Lyophilized |
Reconstitution | Add 100?μL of sterile PBS. Final peptide concentration is 1?mg/mL in PBS. |
Concentration | 1 mg/mL |
Buffer | Final peptide concentration is 1 mg/mL in PBS. |
Handling Advice | Avoid repeated freeze-thaw cycles. |
Storage | -20 °C |
Storage Comment | For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles. |