產(chǎn)品詳情
簡單介紹:
Rabbitanti-HumanImmunoglobulinJPolypeptide,LinkerProteinForImmunoglobulinalphaandmuPolypeptides(IGJ)(C-Term),(JoiningChain)Antibody
詳情介紹:
Immunogen | A synthetic peptide derived from near C-terminus of Human J-chain protein. |
Specificity | This antibody detects Immunoglobulin J chain. Cellular localisation: Cytoplasm. |
Cross-Reactivity (Details) | Species reactivity (tested):Human. |
Purification | Immunoaffinity Chromatography |
Alternative Name | Immunoglobulin J Chain |
Background | J chain is a small glycopeptide with MW of 15?kDa. It is structurally unrelated to heavy or light chains, but is synthesized by all plasma cells that secrete polymeric immunoglobulins. J chain is linked to IgA and IgM by disulfide bonds, however, it has been detected in IgG- and IgD-containing cells. J chains are present in a large proportion of the immunoglobulin-positive cells in the germinal centers of the tonsils and lymph nodes. B cells discrete J chain at an early stage of differentiation with the expression persisting in those cells destined to produce IgA or IgM.Synonyms: IGCJ, IGJ |
Molecular Weight | 15 kDa |
Gene ID | 3512 |
NCBI Accession | NP_653247 |
UniProt | P01591 |
Application Notes | Optimal working dilutions should be determined experimentally by the investigator. |
Restrictions | For Research Use only |
Format | Liquid |
Buffer | PBS,?pH 7.6 with 1?% BSA and less than 0.1?% Sodium Azide |
Preservative | Sodium azide |
Precaution of Use | WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing. |
Storage | 4 °C |
Storage Comment | Store the antibody undiluted at 2-8 °C. DO NOT FREEZE! |