產(chǎn)品詳情
簡單介紹:
Mouseanti-HumanIgMAntibody
詳情介紹:
Immunogen | Recombinant heavy chain of human IgM (IM260 IM373 & ICO-30) was used as the immunogen for the Anti-IgM antibody cocktail. |
Clone | IM260-IM373-ICO-30 |
Isotype | IgG1, IgG2b, kappa |
Purification | Protein G affinity chromatography |
Background | Recognizes a protein of 75?kDa, identified as mu heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), gamma (IgG), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. This mAb is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant. |
Research Area | Secondary Antibodies |
Application Notes |
Optimal dilution of the Anti-IgM antibody cocktail should be determined by the researcher. 1. Staining of formalin-fixed tissues requires boiling tissue sections in 10?mM Citrate buffer,?pH 6.0, for 10-20?min followed by cooling at RT for 20?min |
Restrictions | For Research Use only |
Format | Liquid |
Buffer | Prediluted in 1X PBS with 0.1?mg/mL BSA (US sourced) and 0.05?% sodium azide, *For IHC use only* |
Preservative | Sodium azide |
Precaution of Use | This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
Storage | 4 °C,-20 °C |
Storage Comment | Store the Anti-IgM antibody c°Cktail at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide). |