產(chǎn)品詳情
簡(jiǎn)單介紹:
Iberiotoxin(IbTx)
詳情介紹:
Purpose | Iberiotoxin (IbTx) is a Kca channel inhibitor |
Sequence | pGlu-Phe-Thr-AspVal-Asp-Cys-Ser-Val-Ser-Lys-GIu-Cys-Trp-Ser-Val-Cys-Lys-Asp-Leu-Phe-Gly-Val-Asp-Arg-Gly-Lys-Cys-Met-Gly-Lys-Lys-Cys-Arg-Cys-Tyr-GIn-OHDisulfid e bridges: Cys7-Cys28, Cys13-Cys33, Cys17-Cys35 |
Background | Iberiotoxin (IbTx) is a toxin that was originally isolated from Buthus tamulus scorpion venom. Iberiotoxin inhibits selectively the high conductance Ca2+-activated K+ channel (KCa1.1). This toxin does not affect other types of voltage-dependent K+ channels which are sensitive to the Charybdotoxin. Iberiotoxin is a valuable tool to study specifically Maxi-K channels. |
Molecular Weight | 4230.8 Da |
CAS-No | 129203-60-7 |
Restrictions | For Research Use only |