產(chǎn)品詳情
簡(jiǎn)單介紹:
PCI-24781(Abexinostat)
詳情介紹:
Purpose | PCI-24781 (Abexinostat) is a novel pan-HDAC inhibitor mostly targeting HDAC1 with Ki of 7 nM, modest potent to HDACs 2, 3, 6, and 10 and greater than 40-fold selectivity against HDAC8. Phase 1/2. |
Characteristics |
Source of Compound: synthetic Target: HDAC inhibitor Receptor: HDAC1HDAC3/HDAC6/HDAC2/HDAC10/HDAC8 Status: INN,USAN |
Purification | All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality. |
Purity | 97?% + |
Formula | C21H23N3O5 |
Solubility | 10 mM in DMSO |
Molecular Weight | 397.42 g/mol |
CAS-No | 783355-60-2 |
Application Notes | Optimal working dilution should be determined by the investigator. |
Restrictions | For Research Use only |
Format | Solid |
Storage | -20 °C |
Storage Comment |
For the majority of compounds, they could be dissolved in DMSO or other organic solvent. Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience. Several freeze/thaw cycles should not damage the activity of our small molecule products. However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours. |
Expiry Date | 24 months |