產(chǎn)品詳情

  • 產(chǎn)品名稱：5-Azacytidine

  • 產(chǎn)品型號(hào)：
  • 產(chǎn)品廠商：ArborAssays
  • 產(chǎn)品文檔：
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簡(jiǎn)單介紹：
5-Azacytidine
詳情介紹：
Characteristics DNA Methyltransferase inhibitor
Blocks cell cycle progression at G1
Induces activation of HIV-1 promoter
Background Incorporates into DNA, forming covalent adducts with cellular DNMT1, depleting enzyme activity. Induces demethylation and reactivation of silenced genes. Improves the efficiency of reprogramming of stem cells. Methyltransferases in the presence of azacitidine incorporate it into DNA during replication and into RNA during transcription in the cell. Azacytidine acts as a false substrate and potent inhibitor of methyltransferases leading to reduction of DNA methylation.
CAS-No 320-67-2
Restrictions For Research Use only
Storage -20 °C
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image for 5-Azacytidine (ABIN1439968) 5-Azacytidine